HMEC-1/HMEC-1/HMEC-1/人微血管内皮细胞株

HMEC-1/HMEC-1细胞系/HMEC-1细胞株/HMEC-1人微血管内皮细胞株

Cell line name    HMEC-1
Synonyms    Hmec-1; HMEC1; CDC/EU.HMEC-1; Human Microvascular Endothelial Cell line-1
Accession    CVCL_0307
Resource Identification Initiative    To cite this cell line use: HMEC-1 (RRID:CVCL_0307)
Comments    Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-10636.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSVT).
Derived from site: In situ; Foreskin, skin, dermis; UBERON=UBERON_0001471+UBERON_0002067.
Cell type: Endothelial cell; CL=CL_0000115.
Species of origin    Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell    Male
Age at sampling    <1M
Category    Transformed cell line
STR profile    Source(s): ATCC=CRL-3243

Markers:
Amelogenin    X,Y
CSF1PO    10,12
D5S818    12
D7S820    8,10
D13S317    11,12
D16S539    11,12
TH01    7
TPOX    8,11
vWA    15,17

Run an STR similarity search on this cell line
Publications    
Patent=WO1992017569A1
Ades E.W., Lawley T.J., Candal F.J.
Immortalization of endothelial cells.
Patent number WO1992017569A1, 15-Oct-1992

PubMed=1361507; DOI=10.1111/1523-1747.ep12613748
Ades E.W., Candal F.J., Swerlick R.A., George V.G., Summers S., Bosse D.C., Lawley T.J.
HMEC-1: establishment of an immortalized human microvascular endothelial cell line.
J. Invest. Dermatol. 99:683-690(1992)

PubMed=12453433; DOI=10.1006/mvre.2002.2434
Unger R.E., Krump-Konvalinkova V., Peters K., Kirkpatrick C.J.
In vitro expression of the endothelial phenotype: comparative study of primary isolated cells and cell lines, including the novel cell line HPMEC-ST1.6R.
Microvasc. Res. 64:384-397(2002)