Custom polyclonal antibodies Custom monoclonal antibodies Hybridoma banking Assay development services Drug validation using antibodies
Bioklone Biotech Private Limited是一家通过ISO 9001:2015认证的生物服务提供商,专门从事定制抗体和检测的开发。它在印度和国外的各个行业拥有300多个客户,包括学术界、医院研发部门、诊断和制药公司。自2006年成立以来,Bioklone的愿景就是成为世界上的抗体公司之一。Bioklone在2019年全球健康和制药技术奖中获得“印度最佳定制抗体开发专家”奖。这种认可之所以得以实现,是因为该公司独特的销售主张,包括其终端服务、以客户为中心的方法、及时的交付、高质量和可靠的服务。
Bioklone已成功开发出针对1000多种抗原的定制多克隆和单克隆抗体,包括蛋白质、肽、多糖、药物、小分子和整个细胞。在Bioklone开发的几种具有挑战性的抗体中,有针对靶蛋白上某些氨基酸修饰的高度特异性抗体,包括乙酰化、甲基化、切割、突变和磷酸化。此外,Bioklone还开发了针对几种疫苗的定制抗体,以及癌症、心肌梗死、遗传疾病和罕见疾病以及植物、兽医和人类病原体的生物标记物。作为一家合同研究机构,Bioklone提供端到端服务,包括肽设计、基因克隆、重组蛋白的表达和纯化、兔、小鼠和鸡抗体的开发、抗体纯化、标记和片段化、重组抗体的开发,分析开发解决方案和诊断试剂盒的开发。此外,Bioklone还利用细胞系进行体外试验,以研究细胞活力/增殖。Bioklone在定制抗体市场上占据了一席之地,现在正进军人类抗体和人源化抗体的开发。
Bioklone Biotech Private Limited is an ISO 9001:2015 certified bioservice provider that specializes in the development of customized antibodies and assays. It has over 300 clients across various sectors including academia, R&D divisions of hospitals, diagnostic and pharma companies, in India and abroad. Ever since its inception in 2006, the vision of Bioklone has been to be among the preferred antibody companies in the world. Bioklone was awarded “Best Custom Antibody Development Specialists-India” award in Global Health and Pharma-Technology awards 2019. This recognition has been possible because of the company’s unique selling propositions including its end-end services, customer centric approach, timely deliveries, high quality and reliable services.
Bioklone has successfully developed custom polyclonal and monoclonal antibodies to over 1000 antigens including proteins, peptides, polysaccharides, drugs, small molecules and whole cells. Among the several challenging antibodies developed by Bioklone, are the highly specific antibodies to modifications at certain amino acids along the target protein, including acetylation, methylation, cleavage, mutation and phosphorylation. In addition, Bioklone has developed custom antibodies to several vaccines, biomarkers for conditions including cancers, myocardial infarction, genetic disorders and rare diseases as well as plant, veterinary and human pathogens. As a contract research organization, Bioklone offers end-to-end services, including peptide designing, gene cloning, expression and purification of recombinant proteins, development of antibodies in rabbits, mice and chicken, antibody purification, labelling and fragmentation, development of recombinant antibodies, assay development solutions and development of diagnostic kits. In addition, Bioklone also carries out in vitro assays using cell-lines to study cell viability/proliferation. Having carved its niche in the custom antibody market, Bioklone is now foraying into development of human and humanized antibodies.