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- 2025年12月05日
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- 详细信息
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名：
BIA 2-005; GP 47779
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
29331-92-8
- 规格：
10 mM * 1 mL/5 mg/10 mg/25 mg/50 mg/100 mg/200 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥110.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥100.0 |
| 规格： | 10 mg | 产品价格： | ￥160.0 |
| 规格： | 25 mg | 产品价格： | ￥320.0 |
| 规格： | 50 mg | 产品价格： | ￥500.0 |
| 规格： | 100 mg | 产品价格： | ￥700.0 |
| 规格： | 200 mg | 产品价格： | ￥1061.0 |
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Licarbazepine
CAS No. : 29331-92-8
MCE 国际站：Licarbazepine
产品活性：Licarbazepine (BIA 2-005; GP 47779) 是一种电压门控钠通道 (sodium channel) 阻滞剂，具有抗惊厥和稳定情绪的作用。
研究领域：Membrane Transporter/Ion Channel
作用靶点：Sodium Channel
In Vivo: Eslicarbazepine acetate (ESL) is an oral pro-drug that is rapidly and extensively metabolized by the liver via a hydrolytic first-pass metabolism into S-Licarbazepine, the biologically active drug. The plasma level of the prodrug remains below quantification.
ESL is a potent antiepileptic agent with a spectrum of action essentially limited to partial-onset and generalized tonic-clonic seizures. Its main mechanism of action is by blocking the voltage-gated sodium channel. ESL works by blocking the voltage-gated sodium channel, which play an essential role in the generation and propagation of the epileptic discharge. ESL is well absorbed after oral administration with a bio-availability about 16% higher than that observed after an equivalent dose of Oxcarbazepine (OXC).
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