L-threo-PPMP,207278-87-3

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L-threo-PPMP

CAS No. : 207278-87-3

MCE 国际站：L-threo-PPMP

产品活性：L-threo-PPMP 是一种 GlcT (UDP-Glc: Ceramide β1,1glucosyltransferase) 抑制剂。L-threo-PPMP 抑制鞘糖脂生物合成并诱导细胞凋亡。L-threo-PPMP 具有抗癌活性。

研究领域：Apoptosis

作用靶点：Apoptosis

In Vitro: L-threo-PPMP (0.5-20 μM) induces apoptosis in carcinoma (Colo-205; SKBR3) cells after 6 h and damaging DNA between 24 and 48 h after treatment.
L-threo-PPMP (1-16 μM; 48 hours) includes Caspase-3 activation in breast cancer SKBR3 cells.

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