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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 免疫原:
None
- 亚型:
IgG2b, kappa
- 保存条件:
Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.
- 克隆性:
Monoclonal
- 标记物:
FITC Plus Fluorescent Dye
- 适应物种:
Mouse
- 保质期:
详见产品包装
- 库存:
充足
- 宿主:
Rat
- 应用范围:
FC
- 靶点:
CD44
- 抗体英文名:
FITC Plus Anti-Mouse CD44 (IM7)
- 抗体名:
FITC Plus Anti-Mouse CD44 (IM7)
- 规格:
25ug/100ug
| 规格: | 25ug | 产品价格: | ¥600.0 |
|---|---|---|---|
| 规格: | 100ug | 产品价格: | ¥1200.0 |
经过测试的应用
| Positive FC detected in | mouse splenocytes |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Flow Cytometry (FC) | FC : 0.5 ug per 10^6 cells in 100 μl suspension |
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
FITC-65117 targets CD44 in FC applications and shows reactivity with Mouse samples.
| 经测试应用 | FC |
| 文献引用应用 | FC |
| 经测试反应性 | Mouse |
| 文献引用反应性 | human, mouse |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Rat / IgG2b, kappa |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | CD44 antigen |
| 别名 | CD44, CD44 antigen, CDW44, CSPG8, ECMR III, Epican, HCELL, Heparan sulfate proteoglycan, Hermes antigen, HUTCH I, Hyaluronate receptor, IN, LHR, MC56, MDU2, MDU3, MIC4, MUTCH I, PGP 1, PGP I, Pgp1, Phagocytic glycoprotein 1, Phagocytic glycoprotein I |
| GenBank蛋白编号 | BC051388 |
| 基因名称 | Cd44 |
| Gene ID (NCBI) | 12505 |
| RRID | AB_2883787 |
| 偶联类型 | FITC Plus Fluorescent Dye |
| 最大激发/发射波长 | 495 nm / 524 nm |
| 形式 | Liquid |
| 纯化方式 | Affinity purification |
| UNIPROT ID | P15379 |
| 储存缓冲液 | PBS with 0.09% sodium azide, pH 7.3. |
| 储存条件 | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
背景介绍
CD44 is a type I transmembrane glycoprotein expressed on embryonic stem cells and in various levels on other cell types including connective tissues and bone marrow. CD44 expression is also upregulated in subpopulations of cancer cells and is recognized as a molecular marker for cancer stem cells (PMID: 29747682). It is a cell-surface receptor that mediates cell-cell and cell-matrix interactions through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands (PMID: 10694938). Adhesion with HA plays an important role in cell migration, tumor growth and progression. CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis.
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- 作者
- 内容
- 询问日期
文献和实验| Species | Application | Title |
|---|---|---|
| mouse | FC | Small The Effect of the Nanoparticle Shape on T Cell Activation.Authors - Jiwon Oh |
| mouse | FC | J Control Release Dual-phase nanoscissors disrupt vasculature-breast cancer stem cell crosstalk for breast cancer treatmentAuthors - Yao Qi |
| human | FC | Cell Mol Life Sci Phosphocholine inhibits proliferation and reduces stemness of endometrial cancer cells by downregulating mTOR-c-Myc signalingAuthors - Kunxiang Gong |
| human,mouse | FC | Discov Oncol Preclinical efficacy of CBR-5884 against epithelial ovarian cancer cells by targeting the serine synthesis pathwayAuthors - Kunxiang Gong |
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