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CoraLite® Plus 488-conjugated

MMP-9 (N-terminal) 多克隆抗体 CL488-10375
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  • ¥3200
  • Proteintech已认证
  • CL488-10375
  • 2025年10月13日
  • IF/ICC
  • Rabbit
  • human
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    • 详细信息
    • 技术资料
    • 免疫原

      Recombinant human MMP9 protein

    • 亚型

      IgG

    • 保存条件

      Store at -20°C. Avoid exposure to light. Stable for one year after shipment.

    • 克隆性

      Polyclonal

    • 标记物

      CoraLite® Plus 488 Fluorescent Dye

    • 适应物种

      human

    • 保质期

      详见产品包装

    • 库存

      充足

    • 宿主

      Rabbit

    • 应用范围

      IF/ICC

    • 靶点

      MMP-9 (N-terminal)

    • 抗体英文名

      CoraLite® Plus 488-conjugated MMP-9 (N-terminal) Polyclonal antibody

    • 抗体名

      CoraLite® Plus 488-conjugated MMP-9 (N-terminal) Polyclonal antibody

    • 规格

      100ul

    经过测试的应用

    Positive IF/ICC detected inMCF-7 cells
    Planning an IHC experiment? We recommend our IHCeasy MMP9 Ready-To-Use IHC Kit. MMP9 primary antibody included.

    推荐稀释比

    应用推荐稀释比
    Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
    It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
    Sample-dependent, Check data in validation data gallery.

    产品信息

    CL488-10375 targets MMP-9 (N-terminal) in IF/ICC applications and shows reactivity with human samples.

    经测试应用 IF/ICC
    经测试反应性 human
    免疫原

    CatNo: Ag0552

    Product name: Recombinant human MMP9 protein

    Source: e coli.-derived, PGEX-4T

    Tag: GST

    Domain: 1-100 aa of BC006093

    Sequence: MSLWQPLVLVLLVLGCCFAAPRQRQSTLVLFPGDLRTNLTDRQLAEEYLYRYGYTRVAEMRGESKSLGPALLLLQKQLSLPETGELDSATLKAMRTPRCG

    宿主/亚型 Rabbit / IgG
    抗体类别 Polyclonal
    产品类型 Antibody
    全称 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
    别名 MMP9 (N-terminal), MMP9, 67 kDa matrix metalloproteinase-9, 82 kDa matrix metalloproteinase-9, CLG4B
    计算分子量 707 aa, 78 kDa
    观测分子量 67 kDa, 92 kDa
    GenBank蛋白编号BC006093
    基因名称 MMP-9
    Gene ID (NCBI) 4318
    RRIDAB_2918976
    偶联类型 CoraLite® Plus 488 Fluorescent Dye
    最大激发/发射波长493 nm / 522 nm
    形式Liquid
    纯化方式Antigen affinity purification
    UNIPROT IDP14780
    储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
    储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

    背景介绍

    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue remodeling, and disease processes, such as arthritis or metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. Matrix metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (MMP9, synonyms: GELB, CLG4B) degrades collagens type IV and V. Studies in rhesus monkeys suggest that MMP9 is involved in IL-8-induced mobilization hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. The pro-MMP9 is 92 kDa, and it can be detected a processed form of 68 kDa. This protein can exist as a dimer of 180 kDa (PMID:7492685).

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