- ￥1020 - 2550
- Proteintech
- APC-65138
- 2025年10月13日
- FC
- Mouse
- mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
None
- 亚型：
IgG2a, kappa
- 保存条件：
Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.
- 克隆性：
Monoclonal
- 标记物：
APC Fluorescent Dye
- 适应物种：
mouse
- 保质期：
详见产品包装
- 库存：
充足
- 宿主：
Mouse
- 应用范围：
FC
- 靶点：
NK1.1 (CD161)
- 抗体英文名：
APC Anti-Mouse NK1.1 (CD161) (PK136)
- 抗体名：
APC Anti-Mouse NK1.1 (CD161) (PK136)
- 规格：
25ug/100ug
| 规格： | 25ug | 产品价格： | ￥1020.0 |
|---|---|---|---|
| 规格： | 100ug | 产品价格： | ￥2550.0 |
经过测试的应用
| Positive FC detected in | mouse splenocytes |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Flow Cytometry (FC) | FC : 0.13 ug per 10^6 cells in 100 μl suspension |
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
APC-65138 targets NK1.1 (CD161) in FC applications and shows reactivity with mouse samples.
| 经测试应用 | FC |
| 经测试反应性 | mouse |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Mouse / IgG2a, kappa |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | killer cell lectin-like receptor subfamily B member 1A |
| 别名 | Klrb1a, CD161a, PK136, Nkrp1a, NK1.1 |
| GenBank蛋白编号 | BC120707 |
| 基因名称 | NK1.1 |
| Gene ID (NCBI) | 17057 |
| RRID | AB_2883019 |
| 偶联类型 | APC Fluorescent Dye |
| 最大激发/发射波长 | 650 nm / 660 nm |
| 形式 | Liquid |
| 纯化方式 | Affinity purification |
| UNIPROT ID | P27811 |
| 储存缓冲液 | PBS with 0.09% sodium azide and 0.1% gelatin, pH 7.2. |
| 储存条件 | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
背景介绍
NK1.1 (CD161), also known as KLRB1 or NKR-P1A, is a type II transmembrane C-type lectin-like receptor and is expressed on the cell membrane as disulfide-linked homodimer (PMID: 8077657). It is expressed by the majority of NK cells and subsets of peripheral T cells, including both CD4+ and CD8+ T cells, and is expressed preferentially on adult T cells with a "memory" antigenic phenotype (PMID: 8077657; 22566826). Expression of CD161 correlates with the cytotoxic function of CD16+ NK cells, and ligation of CD161 with its ligand LLT1 inhibits NK cell cytotoxicity and cytokine secretion (PMID: 29686665).
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