- ￥1250 - 3120
- Proteintech
- APC-65089
- 2025年10月13日
- FC (Intra)
- Mouse
- mouse
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
None
- 亚型：
IgG1, kappa
- 保存条件：
Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.
- 克隆性：
Monoclonal
- 标记物：
APC Fluorescent Dye
- 适应物种：
mouse
- 保质期：
详见产品包装
- 库存：
充足
- 宿主：
Mouse
- 应用范围：
FC (Intra)
- 靶点：
Foxp3
- 抗体英文名：
APC Anti-Mouse Foxp3 (3G3)
- 抗体名：
APC Anti-Mouse Foxp3 (3G3)
- 规格：
25ug/100ug
| 规格： | 25ug | 产品价格： | ￥1250.0 |
|---|---|---|---|
| 规格： | 100ug | 产品价格： | ￥3120.0 |
经过测试的应用
| Positive FC (Intra) detected in | mouse splenocytes |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.06 ug per 10^6 cells in 100 μl suspension |
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
APC-65089 targets Foxp3 in FC (Intra) applications and shows reactivity with mouse samples.
| 经测试应用 | FC (Intra) |
| 文献引用应用 | FC (Intra) |
| 经测试反应性 | mouse |
| 文献引用反应性 | mouse |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Mouse / IgG1, kappa |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | forkhead box P3 |
| 别名 | sf, scurfin, JM2, forkhead box P3, 3G3 |
| GenBank蛋白编号 | BC132333 |
| 基因名称 | Foxp3 |
| Gene ID (NCBI) | 20371 |
| RRID | AB_2882984 |
| 偶联类型 | APC Fluorescent Dye |
| 最大激发/发射波长 | 650 nm / 660 nm |
| 形式 | Liquid |
| 纯化方式 | Affinity purification |
| UNIPROT ID | Q99JB6 |
| 储存缓冲液 | PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3. |
| 储存条件 | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
背景介绍
Foxp3 (forkhead box P3), also named as IPEX, JM2 and scurfin, is a member of the forkhead transcription factor family and is essential for normal immune homeostasis (PMID: 11138001; 20429413). Foxp3 is specifically expressed in CD4+ CD25+ regulatory T cells and is crucial for their development and suppressive activity (PMID: 12612578; 12612581). In scurfy mouse, disruption of Foxp3 results in the fatal lymphoproliferative disorder attributed to the lack of an immune-suppressive component in the immune system (PMID: 25683611; 11138001). Similar to mice, genetic defects in human Foxp3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) which also known as X-linked autoimmunity-immunodeficiency syndrome (PMID: 11137993).
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验| Species | Application | Title |
|---|---|---|
| mouse | FC (Intra) | Drug Deliv Sonodynamical reversion of immunosuppressive microenvironment in prostate cancer via engineered exosomes.Authors - Dingyi Wang |
| mouse | FC (Intra) | Phytomedicine Multi-material basis and multi-mechanisms of the Dahuang Zhechong pill for regulating Treg/Th1 balance in hepatocellular carcinoma.Authors - Li Wu |
| mouse | FC (Intra) | ACS Nano Bioengineered Nanospores Selectively Blocking LC3-Associated Phagocytosis in Tumor-Associated Macrophages Potentiate Antitumor ImmunityAuthors - Yunkai Shang |
，表现出Th1、Th2和TFH等具有传统功能的细胞亚群。导致Foxp3下调的关键因素包括高水平的炎症因子内环境，如可诱导效应性T细胞产生的细胞因子：IL-6和IFN-gamma。Tregs 细胞中Foxp3的表达分析CD4+CD25+ Treg 细胞中Foxp3 +细胞群表明与Foxp3+Treg完全重合。使用Foxp3鉴定Treg用Anti-Mouse CD4 FITC、Anti-Mouse CD25 APC和Anti-Mouse/Rat Foxp3 PE 标记BALB/c小鼠 脾细胞. 右上
Stimulation of Anti-HIV-1 Cytotoxic T Lymphocytes by Dendritic Cells
Dendritic cells (DC) are highly specialized antigen-presenting cells (APC) in both primary and secondary T-cell responses. This may be related to their expression of high levels of MHC class I and II antigens (1 -4 ), costimulatory
Isolation and Propagation of Mouse Liver-Derived Dendritic Cells
Dendritic cells (DC) are highly specialized antigen-presenting cells (APC) derived from precursors within the bone marrow (BM). They are distributed ubiquitously throughout the body, and are few in number (1 ). They are classified
技术资料暂无技术资料 索取技术资料
