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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
None
- 亚型:
IgG1, lambda
- 保存条件:
Store at 2-8°C. Stable for one year after shipment.
- 克隆性:
Monoclonal
- 标记物:
Unconjugated
- 适应物种:
mouse
- 保质期:
详见产品包装
- 库存:
充足
- 宿主:
Rat
- 应用范围:
FC
- 靶点:
CD25/IL-2RA
- 抗体英文名:
Anti-Mouse CD25/IL-2RA (PC61.5)
- 抗体名:
Anti-Mouse CD25/IL-2RA (PC61.5)
- 规格:
100ug/500ug
| 规格: | 100ug | 产品价格: | ¥960.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥2610.0 |
经过测试的应用
| Positive FC detected in | Anti-CD3 and Anti-CD28 stimulated mouse splenocytes |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Flow Cytometry (FC) | FC : 0.5 ug per 10^6 cells in 100 μl suspension |
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
65137-1-Ig targets CD25/IL-2RA in FC applications and shows reactivity with mouse samples.
| 经测试应用 | FC |
| 经测试反应性 | mouse |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Rat / IgG1, lambda |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | interleukin 2 receptor, alpha chain |
| 别名 | CD25, Il-2ra, Il2ra, IL-2R subunit alpha, Il2r |
| GenBank蛋白编号 | BC114437 |
| 基因名称 | CD25 |
| Gene ID (NCBI) | 16184 |
| RRID | AB_2918424 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein G purification |
| UNIPROT ID | P01590 |
| 储存缓冲液 | PBS with 0.09% sodium azide, pH 7.3. |
| 储存条件 | Store at 2-8°C. Stable for one year after shipment. |
背景介绍
Proliferation of T lymphocytes is triggered by the interaction of IL-2 with its specific receptor following T lymphocyte activation. The receptor for IL-2 has three forms, generated by different combinations of three different proteins, the alpha chain (IL-2R alpha), the beta chain (IL-2R beta), and the gamma chain (IL-2R gamma) (PMID: 8476561). IL-2R alpha (also known as CD25) is a type I transmembrane protein present on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes. CD25 is also found on natural CD4+Foxp3+ Treg cells (PMID: 22585674).
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