- ￥1350 - 3000
- Proteintech
- 23495-1-AP
- 2025年10月13日
- WB, ELISA
- Rabbit
- human, mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant human UGT1A1 protein
- 亚型：
IgG
- 保存条件：
Store at -20°C. Stable for one year after shipment.
- 克隆性：
Polyclonal
- 标记物：
Unconjugated
- 适应物种：
human, mouse
- 保质期：
详见产品包装
- 库存：
充足
- 宿主：
Rabbit
- 应用范围：
WB, ELISA
- 靶点：
UGT1A1
- 抗体英文名：
UGT1A1 Polyclonal antibody
- 抗体名：
UGT1A1 Polyclonal antibody
- 规格：
50ul/100ul/150ul
| 规格： | 50ul | 产品价格： | ￥1350.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥2200.0 |
| 规格： | 150ul | 产品价格： | ￥3000.0 |
经过测试的应用
| Positive WB detected in | mouse liver tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
23495-1-AP targets UGT1A1 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, ELISA |
| 文献引用应用 | WB, IHC, IF |
| 经测试反应性 | human, mouse |
| 文献引用反应性 | human, mouse, rat |
| 免疫原 |
CatNo: Ag19001 Product name: Recombinant human UGT1A1 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 26-263 aa of BC128415 Sequence: HAGKILLIPVDGSHWLSMLGAIQQLQQRGHEIVVLAPDASLYIRDGAFYTLKTYPVPFQREDVKESFVSLGHNVFENDSFLQRVIKTYKKIKKDSAMLLSGCSHLLHNKELMASLAESSFDVMLTDPFLPCSPIVAQYLSLPTVFFLHALPCSLEFEATQCPNPFSYVPRPLSSHSDHMTFLQRVKNMLIAFSQNFLCDVVYSPYATLASEFLQREVTVQDLLSSASVWLFRSDFVKD |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | UDP glucuronosyltransferase 1 family, polypeptide A1 |
| 别名 | GNT1, HUG BR1, UDPGT, UDPGT 1 1, UGT 1A, UGT1, UGT1 01, UGT1*1, UGT1.1, UGT1A, UGT1A1 |
| 计算分子量 | 533 aa, 60 kDa |
| 观测分子量 | 50-60 kDa, 65-70 kDa |
| GenBank蛋白编号 | BC128415 |
| 基因名称 | UGT1A1 |
| Gene ID (NCBI) | 54658 |
| RRID | AB_2879286 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen Affinity purified |
| UNIPROT ID | P22309 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
UDP-glucuronosyltransferase 1A1 (UGT1A1) is one of nine transferases encoded on the UGT1 locus. Developmental regulation of the UGT1A1 gene is an important process that is needed to achieve normal levels of serum total bilirubin (TB). UGT1A1 is a 50-60 kda member of the UGT1A subfamily, and can be detected as 65-70kda band after posttranslational modification.
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文献和实验| Species | Application | Title |
|---|---|---|
| human | WB,IF | J Mol Biol Silencing of Aberrant Secretory Protein Expression by Disease-Associated Mutations.Authors - Elena B Tikhonova |
| rat | WB,IHC | Phytomedicine Oleanolic acid alleviates ANIT-induced cholestatic liver injury by activating Fxr and Nrf2 pathways to ameliorate disordered bile acids homeostasis.Authors - Jianming Liu |
| human,rat | WB,IHC | Phytomedicine NRF2 and FXR dual signaling pathways cooperatively regulate the effects of oleanolic acid on cholestatic liver injuryAuthors - Jianming Liu |
| mouse | WB | Pathogens Dysregulated Glucuronidation of Bilirubin Exacerbates Liver Inflammation and Fibrosis in Schistosomiasis Japonica through the NF-κB Signaling PathwayAuthors - Qingkai Xue |
| mouse | WB | Front Nutr The Protective Effect of Sulforaphane on Dextran Sulfate Sodium-Induced Colitis Depends on Gut Microbial and Nrf2-Related Mechanism.Authors - Canxia He |
| human | WB | Metabolites The Glycosyltransferase Pathway: An Integrated Analysis of the Cell MetabolomeAuthors - Yannick Audet-Delage |
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