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ANT1/2 多克隆抗体 17796-1-AP

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  • ¥1350 - 3000
  • Proteintech已认证
  • 17796-1-AP
  • 2025年10月13日
  • WB, IHC, ELISA
  • Rabbit
  • human, mouse, rat
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      Recombinant human SLC25A5 protein

    • 亚型

      IgG

    • 保存条件

      Store at -20°C. Stable for one year after shipment.

    • 克隆性

      Polyclonal

    • 标记物

      Unconjugated

    • 适应物种

      human, mouse, rat

    • 保质期

      详见产品包装

    • 库存

      充足

    • 宿主

      Rabbit

    • 应用范围

      WB, IHC, ELISA

    • 靶点

      ANT1/2

    • 抗体英文名

      ANT1/2 Polyclonal antibody

    • 抗体名

      ANT1/2 Polyclonal antibody

    • 规格

      50ul/100ul/150ul

    规格:50ul产品价格:¥1350.0
    规格:100ul产品价格:¥2200.0
    规格:150ul产品价格:¥3000.0

    经过测试的应用

    Positive WB detected inK-562 cells, HepG2 cells, mouse brain tissue, mouse heart tissue, mouse liver tissue, mouse kidney tissue, rat brain tissue, rat heart tissue, rat liver tissue
    Positive IHC detected inhuman liver tissue, human liver cancer tissue, mouse heart tissue, mouse kidney tissue, human cervical cancer tissue, human stomach cancer tissue
    Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
    Planning an IHC experiment? We recommend our IHCeasy SLC25A5 Ready-To-Use IHC Kit. SLC25A5 primary antibody included.

    推荐稀释比

    应用推荐稀释比
    Western Blot (WB)WB : 1:1000-1:6000
    Immunohistochemistry (IHC)IHC : 1:250-1:1000
    It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
    Sample-dependent, Check data in validation data gallery.

    产品信息

    17796-1-AP targets ANT1/2 in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

    经测试应用 WB, IHC, ELISA
    文献引用应用WB, IHC
    经测试反应性 human, mouse, rat
    文献引用反应性human, mouse, rat
    免疫原

    CatNo: Ag11956

    Product name: Recombinant human SLC25A5 protein

    Source: e coli.-derived, T-HIS

    Tag: 6*His

    Domain: 1-298 aa of BC056160

    Sequence: MTDAAVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRAAYFGIYDTAKGMLPDPKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYT

    宿主/亚型 Rabbit / IgG
    抗体类别 Polyclonal
    产品类型 Antibody
    全称 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
    别名 SLC25A5, ANT 2, ADP/ATP translocase 2, N-terminally processed, ADP/ATP translocase 2, ADP,ATP carrier protein 2
    计算分子量 298 aa, 33 kDa
    观测分子量 30-32 kDa, 60 kDa
    GenBank蛋白编号BC056160
    基因名称 SLC25A5
    Gene ID (NCBI) 292
    RRIDAB_2190358
    偶联类型 Unconjugated
    形式Liquid
    纯化方式Antigen affinity purification
    UNIPROT IDP05141
    储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
    储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

    背景介绍

    Adenine nucleotide translocators (ANTs) are mitochondrial carrier proteins that exchange ATP and ADP between the cytoplasm and the mitochondrial matrix. Four isoforms of ANT were identified: ANT1 (encoded by SLC25A4) is highly expressed in different tissues; ANT2 (encoded by SLC25A5) is predominantly expressed in proliferating, regenerating, or undifferentiated cells; ANT3 is ubiquitously expressed; ANT4 is mainly expressed in testis and germ cells. This antibody recognizes both of ANT1 and ANT2. The predicted molecular weight of ANT1/2 protein is around 32 kDa. While 60 kDa protein can also be observed, which has been proposed as the dimer of ANT1/2. (22423112)

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    图标文献和实验
    该产品被引用文献
    SpeciesApplicationTitle
    WB

    Elife

    Legionella pneumophila modulates host energy metabolism by ADP-ribosylation of ADP/ATP translocases.

    Authors - Jiaqi Fu
    mouseWB

    PLoS Genet

    Novel insights into SLC25A46-related pathologies in a genetic mouse model.

    Authors - Maria Eirini Terzenidou
    humanIHC

    Mol Cell Proteomics

    Proteomics of skin proteins in psoriasis: from discovery and verification in a mouse model to confirmation in humans.

    Authors - Kathleen C Lundberg
    ratWB

    Exp Neurol

    Physical exercise ameliorates psychiatric disorders and cognitive dysfunctions by hippocampal mitochondrial function and neuroplasticity in post-traumatic stress disorder.

    Authors - Jin-Hee Seo
    mouseWB

    J Proteome Res

    Proteomic Identification of the SLC25A46 Interactome in Transgenic Mice Expressing SLC25A46-FLAG.

    Authors - Vasiliki-Iris Perivolidi
    humanWB

    Biology (Basel)

    TERT Promoter Revertant Mutation Inhibits Melanoma Growth through Intrinsic Apoptosis.

    Authors - Yanbing Wang
    相关实验
    • 有适合免疫沉淀IP的GST抗体吗?

      因此,综合来说,EarthOx的GST标签抗体 (货号#E022040)是一款同时具有高特异性、高灵敏度、多应用类型以及性价比的GST标签抗体。同时,我们也提供其他品牌的GST标签抗体,如Proteintech的GST多克隆抗体 ――GST PolyClonal Antibody(货号#10000-0-AP)以及Abcam、Santa等多种GST标签抗体产品。更多GST标签抗体以及其他如His、HA、Myc、GFP、Flag等其他标签抗体,请电话垂询。美国EarthOx品牌是一家提供高性价比免疫学和细胞

    • Microarray Approaches for Analysis of Cell Cycle Regulatory Genes

      Cell cycle phase Mammalian Yeast G0/G1 AP-1 family (FOS, JUN)

    • 线粒体和凋亡

      同时,Apaf―1可以激活原形的caspase―9,形成细胞色素C/Apaf―1/caspase―9复合体,即凋亡复合体(apoptosome)。该复合体水解并激活下游的caspase通路如caspase―3等。     凋亡复合体的形成是凋亡信号启动的关键步骤。目前发现激活的癌基因可以辅助凋亡复合体的形成,比如腺病毒EIA可以上调Apaf―1和caspase―9,E2F1可以上调Apaf―1的表达。Apaf―1的释放可促进凋亡复合体的形成,对凋亡的启动起促进作用。目前的研究认为,细胞

    图标技术资料

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    文献支持
    ANT1/2 多克隆抗体 17796-1-AP
    ¥1350 - 3000