FKBP1A 多克隆抗体

免疫组织化学（IHC）已验证样本:Human cervical cancer

IHC 1:50-1:300, ELISA 1:5000-1:10000

Polyclonal

IgG

Fusion protein of human FKBP1A

FKBP1A

12 kDa FK506-binding protein;12 kDa FKBP;Calstabin 1;FK506 binding protein 1;FK506 binding protein 12;FK506 binding protein 1A (12kD);FK506 binding protein 1A 12kDa;FK506 binding protein 1A;FK506 binding protein T cell 12 kD;FK506 binding protein;T cell;12 kD;FK506 binding protein12;FK506-binding protein 1A;FKB1A;FKBP 12;FKBP 1A;FKBP-12;FKBP-1A;FKBP1;FKBP12;FKBP12 Exip3;FKBP12C;fkbp1a;Immunophilin FKBP12;Peptidyl prolyl cis trans isomerase;Peptidyl-prolyl cis-trans isomerase FKBP1A;PKC12;PKCI2;PPIase;PPIase FKBP1A;Protein kinase C inhibitor 2;Rotamase抗体

P62942

Cytoplasm.

0.96 mg/mL

在-20℃下储存有效期为12个月。 避免冻融循环。

PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Antigen affinity purification

Cancer; Immunology

Unconjugated

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed.