SCRN2 多克隆抗体

Western Blot（WB）已验证样本:Mouse small intestines
免疫组织化学（IHC）已验证样本:Human esophagus cancer,Human tonsil

WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000

Polyclonal

IgG

Fusion protein of human SCRN2

SCRN2

scrn2;SCRN2;Secernin 2;Secernin-2;Ses2抗体

Q96FV2

47 kDa

Refer to figures

Extracellular region or secreted,extracellular exosome

0.84 mg/mL

在-20℃下储存有效期为12个月。 避免冻融循环。

PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Antigen affinity purification

Cell Biology

Unconjugated

The SCRN (Secernin) gene family has three vertebrate paralogs, i.e. SCRN1, SCRN2 and SCRN3, which are closely linked to human HOXA, HOXB and HOXD cluster, respectively. SCRN2 (secernin-2) is a 425 amino acid protein that belongs to the peptidase C69 family and the Secernin subfamily. Vertebrate SCRN genes showed a topology of the form (A)(BC), i.e. (Hsa2 Hsa7)(Hsa17), with SCRN2 falling outside the SCRN3–SCRN1 cluster. The SCRN2 gene is conserved in dog, cow, mouse, rat and zebrafish, and maps to human chromosome 17q21.32. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Chromosome 17 is linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.