IGHA1 多克隆抗体

免疫组织化学（IHC）已验证样本:Human cervical cancer,Human colorectal cancer

IHC 1:50-1:300, ELISA 1:5000-1:10000

Polyclonal

IgG

Fusion protein of human IGHA1

IGHA1

FLJ14473;FLJ35065;FLJ35500;FLJ36402;FLJ39698;FLJ40001;FLJ41548;FLJ41552;FLJ41789;FLJ43248;FLJ43594;FLJ44293;FLJ46028;FLJ46621;FLJ46724;FLJ46811;FLJ46824;FLJ90170;Ig alpha 1 chain C region;IgA1;IGHA1;immunoglobulin heavy constant alpha 1;MGC102857抗体

P01876

0.9 mg/mL

在-20℃下储存有效期为12个月。 避免冻融循环。

PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Antigen affinity purification

Cancer; Immunology

Unconjugated

Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268). Ig alpha is the major immunoglobulin class in body secretions (PubMed:2241915).