IL37 多克隆抗体

免疫组织化学（IHC）已验证样本:Human brain

IHC 1:20-1:100, ELISA 1:5000-1:10000

Polyclonal

IgG

Synthetic peptide of human IL37

IL37

FIL1;FIL1 zeta;FIL1(ZETA);FIL1Z;IL 1 zeta;IL 1F7;IL 1F7b (IL 1H4;IL 1H;IL 1RP1);IL 1H4;IL 1RP1;IL 1X;IL 1X protein;IL-1 zeta;IL-1F7;IL-1H;IL-1H4;IL-1RP1;IL-1X;IL-37;IL1F7 (canonical product IL 1F7b);IL1F7;IL1F7;IL1H4;IL1RP1;Interleukin 1 family member 7;interleukin 1 family;member 7 (zeta);Interleukin 1 homolog 4;Interleukin 1 related protein;Interleukin 1 superfamily z;Interleukin 1 zeta;Interleukin 37;Interleukin-1 family member 7;Interleukin-1 homolog 4;Interleukin-1 zeta;Interleukin-1-related protein;Interleukin-23抗体

Q9NZH6

Cytoplasm>cytosol. Nucleus. Secreted. Stimulation with IL1B leads to colocalization with SMAD3 mostly in perinuclear regions. Only the CASP1-cleaved mature form translocates into the nucleus upon LPS stimulation.

1.44 mg/mL

在-20℃下储存有效期为12个月。 避免冻融循环。

PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Antigen affinity purification

Cancer; Immunology

Unconjugated

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported. IL37 (Interleukin 37) is a Protein Coding gene. Diseases associated with IL37 include Rheumatoid Arthritis. Among its related pathways are Innate Immune System and Toll-Like receptor Signaling Pathways. GO annotations related to this gene include cytokine activity and interleukin-1 receptor binding. An important paralog of this gene is IL36G.