KLF1 多克隆抗体

免疫组织化学（IHC）已验证样本:Human esophagus cancer,Human brain

IHC 1:50-1:100, ELISA 1:2000-1:5000

Polyclonal

IgG

Synthetic peptide of human KLF1

KLF1

CDAN4;EKLF;EKLF PEN;Erythroid krueppel like transcription factor (EKLF) (Erythroid transcription factor);Erythroid krueppel-like transcription factor;Erythroid Kruppel like factor;Erythroid specific transcription factor EKLF;HBFQTL6;Human erythroid-specific transcription factor EKLF mRNA complete cds;INLU;Klf1;KLF1;Krueppel-like factor 1;Kruppel like factor 1 (erythroid)抗体

Q13351

Nucleus. Colocalizes with SUMO1 in nuclear speckles.

0.96 mg/mL

在-20℃下储存有效期为12个月。 避免冻融循环。

PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Antigen affinity purification

Cancer; Epigenetics and Nuclear Signaling

Unconjugated

This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype.KLF1 (Kruppel Like Factor 1) is a Protein Coding gene. Diseases associated with KLF1 include Dyserythropoietic Anemia, Congenital, Type Iv and Hereditary Persistence Of Fetal Hemoglobin-Sickle Cell Disease Syndrome. Among its related pathways are Hematopoietic Stem Cell Differentiation. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and core promoter proximal region sequence-specific DNA binding. An important paralog of this gene is KLF4.