ELOC 多克隆抗体

免疫组织化学（IHC）已验证样本:Human breast cancer,Human ovarian cancer

IHC 1:50-1:300, ELISA 1:5000-1:10000

Polyclonal

IgG

Fusion protein of human ELOC

ELOC

Elongin C;Transcription Elongation Factor B (SIII); Polypeptide 1 (15kDa; Elongin C);RNA Polymerase II Transcription Factor SIII Subunit C;Transcription Elongation Factor B Polypeptide 1;Transcription Elongation Factor B Subunit 1;Elongin 15 KDa Subunit;SIII P15.抗体

Q15369

Cytosol,Nucleus,elongin complex,nucleoplasm

0.96 mg/mL

在-20℃下储存有效期为12个月。 避免冻融循环。

PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Antigen affinity purification

Epigenetics and Nuclear Signaling

Unconjugated

This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been identified.