RUVBL1 多克隆抗体

Western Blot（WB）已验证样本:Raji,K562
免疫组织化学（IHC）已验证样本:Human esophagus cancer,Human thyroid cancer

WB 1:1000-1:5000, IHC 1:50-1:300, ELISA 1:5000-1:10000

Polyclonal

IgG

Fusion protein of human RUVBL1

RUVBL1

49 kDa TATA box binding protein interacting protein;49 kDa TATA box-binding protein-interacting protein;49 kDa TBP interacting protein ;49 kDa TBP-interacting protein;54 kDa erythrocyte cytosolic protein;ECP-54;ECP54;ERYTHROCYTE CYTOSOLIC PROTEIN; 54-KD;INO80 complex subunit H;NMP 238;Nuclear matrix protein 238;Pontin 52;PONTIN;RuvB like 1;RuvB like AAA ATPase 1;RuvB-like 1;RUVB1;RUVBL1;RVB1;TAP54 alpha ;TAP54-alpha;TIP49;TIP49a;TIP60 associated protein 54 alpha;TIP60-associated protein 54-alpha抗体

Q9Y265

50 kDa

Refer to figures

Nucleus matrix. Nucleus>nucleoplasm. Cytoplasm. Membrane. Cytoplasm>cytoskeleton>centrosome. Mainly localized in the nucleus, associated with nuclear matrix or in the nuclear cytosol, although it is also present in the cytoplasm and associated with the cell membranes. In prophase and prometaphase it is located at the centrosome and the branching microtubule spindles. After mitotic nuclear membrane disintigration it accumulates at the centrosome and sites of tubulin polymerization. As cells pass through metaphase and into telophase it is located close to the centrosome at the early phase of tubulin polymerization. In anaphase it accumulates at the zone of tubule interdigitation. In telophase it is found at polar tubule overlap, and it reappears at the site of chromosomal decondensation in the daughter cells.

1.5 mg/mL

在-20℃下储存有效期为12个月。 避免冻融循环。

PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Antigen affinity purification

Cancer; Epigenetics and Nuclear Signaling

Unconjugated

This gene encodes a protein that has both DNA-dependent ATPase and DNA helicase activities and belongs to the ATPases associated with diverse cellular activities (AAA+) protein family. The encoded protein associates with several multisubunit transcriptional complexes and with protein complexes involved in both ATP-dependent remodeling and histone modification. Alternate splicing results in multiple transcript variants.