C12orf40 多克隆抗体

免疫组织化学（IHC）已验证样本:Human liver cancer,Human esophagus cancer

IHC 1:40-1:200, ELISA 1:5000-1:10000

Polyclonal

IgG

Fusion protein of human C12orf40

C12orf40

C12orf40;Chromosome 12 open reading frame 40;CL040;FLJ40126;Uncharacterized protein C12orf40抗体

Q86WS4

1 mg/mL

在-20℃下储存有效期为12个月。 避免冻融循环。

PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Antigen affinity purification

Cell Biology

Unconjugated

Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The C12orf40 gene product has been provisionally designated C12orf40 pending further characterization.