LMNB1 多克隆抗体

Western Blot（WB）已验证样本:Hela,HT29,Human fetal liver,Human testis,231,K562,Human bladder
免疫组织化学（IHC）已验证样本:Human tonsil,Human liver cancer

WB 1:1000-1:5000, IHC 1:100-1:300, ELISA 1:2000-1:10000

Polyclonal

IgG

Fusion protein of human LMNB1

LMNB1

ADLD;lamin B1;Lamin-B1;LMN;LMN2;LMNB;Lmnb1;LMNB1;MGC111419;OTTHUMP00000159218抗体

P20700

67 kDa

Refer to figures

Nucleus inner membrane.

0.5 mg/mL

在-20℃下储存有效期为12个月。 避免冻融循环。

PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Antigen affinity purification

Cancer; Cell Biology; Signal Transduction; Tags and Cell Markers

Unconjugated

The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD).