DUSP11 多克隆抗体

免疫组织化学（IHC）已验证样本:Human liver cancer

IHC 1:30-150, ELISA 1:2000-10000

Polyclonal

IgG

Full length fusion protein

DUSP11

Dual specificity phosphatase 11;Dual specificity protein phosphatase 11;DUS11;DUSP11;Phosphatase that interacts with RNA/RNP complex 1;PIR1;RNA/RNP complex 1 interacting;RNA/RNP complex interacting phosphatase;RNA/RNP complex-1-interacting phosphatase;RNA/RNP complex1 intereracting phosphatase;Serine/threonine specific protein phosphatase抗体

O75319

Nucleus.

1.5 mg/mL

在-20℃下储存有效期为12个月。 避免冻融循环。

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Affinity purification

Epigenetics and Nuclear Signaling; Signal transduction

Unconjugated

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and sub细胞定位, and different modes of inducibility of their expression by extracellular stimuli. This gene product is localized to the nucleus and binds directly to RNA and splicing factors, and thus it is suggested to participate in nuclear mRNA metabolism.