Claudin 7 多克隆抗体

Western Blot（WB）已验证样本:Human liver
免疫组织化学（IHC）已验证样本:Human colon cancer,Human stomach cancer

WB 1:1000-1:3000, IHC 1:50-1:150

Polyclonal

IgG

Synthetic peptide of human CLDN7

CLDN7

CEPTR L2;CEPTRL 2;CEPTRL2;Claudin 1;Claudin 9;Claudin-7;Claudin1;Claudin7;Claudin9;CLD7;CLDN 7;CLDN-7;CLDN7;Clostridium perfringens enterotoxin receptor like 2;CPETR L2;CPETRL 2;CPETRL2;Hs.84359抗体

O95471

23kDa

Cell membrane. Lateral cell membrane. Cell junction>tight junction. Co-localizes with EPCAM at the lateral cell membrane and tight junction.

0.3 mg/mL

在-20℃下储存有效期为12个月。 避免冻融循环。

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Affinity purification

Cancer; Signal Transduction

Unconjugated

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.