CK-6A/B/C 多克隆抗体

免疫组织化学（IHC）已验证样本:Human breast cancer,Human ovarian cancer

IHC 1:50-1:200

Polyclonal

IgG

Synthetic peptide of human KRT6A/KRT6B/KRT6C

KRT6A/KRT6B/KRT6C

K6A;K6C;K6D;CK6A;CK6C;CK6D;KRT6C;KRT6D;K6B;PC2;CK6B;CK-6B;KRTL1;K6E;KRT6E抗体

P02538,P04259,P48668

Cytoskeleton,intermediate filament,keratin filament,Cytosol,Extracellular region or secreted,extracellular exosome

0.4 mg/mL

在-20℃下储存有效期为12个月。 避免冻融循环。

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Affinity purification

Cancer; Signal Transduction; Tags and Cell Markers

Unconjugated

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.