GREM1 多克隆抗体

Western Blot（WB）已验证样本:Mouse testis

WB 1:500-1:2000

Polyclonal

IgG

Recombinant protein of human GREM1

GREM1

BMP antagonist 1;Cell proliferation inducing gene 2 protein;Cell proliferation-inducing gene 2 protein;CKTSF1B1;colorectal adenoma and carcinoma 1;Cysteine knot superfamily 1;Cysteine knot superfamily 1;BMP antagonist 1;Cysteine knot superfamily BMP antagonist 1;DAN domain family member 2;DAND2;Down regulated in Mos-transformed cells protein;Down-regulated in Mos-transformed cells protein;DRM;grem1;GREM1;Gremlin 1 homolog;cysteine knot superfamily;Gremlin 1 like protein;Gremlin 1;cysteine knot superfamily;homolog;GREMLIN;Gremlin-1;Gremlin1;IHG-2;IHG2;Increased in high glucose 2;Increased in high glucose protein 2;PIG2;Proliferation inducing gene 2;proliferation inducing gene 2 protein抗体

O60565

21kDa

Secreted.

0.3 mg/mL

在-20℃下储存有效期为12个月。 避免冻融循环。

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Affinity purification

Signal Transduction; Stem Cells

Unconjugated

This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.