DUSP22 多克隆抗体

免疫组织化学（IHC）已验证样本:Human thyroid cancer

IHC 1:50-1:200

Polyclonal

IgG

Recombinant protein of human DUSP22

DUSP22

Dual specificity protein phosphatase 22;DUS22;Dusp22;JNK stimulatory phosphatase 1;JNK-stimulatory phosphatase-1;JSP 1;JSP-1;JSP1;LMW DSP2;LMW-DSP2;Low molecular weight dual specificity phosphatase 2;MAP kinase phosphatase x;Mitogen activated protein kinase phosphatase x;Mitogen-activated protein kinase phosphatase x;MKP-x;MKPX抗体

Q9NRW4

Cytoplasm. Nucleus.

0.4 mg/mL

在-20℃下储存有效期为12个月。 避免冻融循环。

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Affinity purification

Cell Biology; Signal Transduction

Unconjugated

Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. DUSP22 dephosphorylates ERK2 MAP kinase and JNK. DUSP22 displays highest in thymus, but it is also detectable in monocytes and lymphocytes.