Cathepsin E 多克隆抗体

Western Blot（WB）已验证样本:Mouse stomach
免疫组织化学（IHC）已验证样本:Human ovarian cancer,Human liver cancer

WB 1:500-1:2000, IHC 1:100-1:300

Polyclonal

IgG

Recombinant protein of human CTSE

CTSE

CATE;CATE;Cathepsin E;Cathepsin E form II;CTSE;Erythrocyte membrane aspartic proteinase;Slow moving proteinase抗体

P14091

43kDa

Endosome. The proenzyme is localized to the endoplasmic reticulum and Golgi apparatus, while the mature enzyme is localized to the endosome.

0.6 mg/mL

在-20℃下储存有效期为12个月。 避免冻融循环。

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Affinity purification

Cancer; Immunology

Unconjugated

The protein encoded by this gene is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease, which is a member of the peptidase C1 family, has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest 浓度 in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears, therefore, to be an oncofetal antigen. Transcript variants utilizing alternative polyadenylation signals and two transcript variants encoding different isoforms exist for this gene.