PAWR 多克隆抗体

Western Blot（WB）已验证样本:Hela,A549
免疫组织化学（IHC）已验证样本:Human colon cancer,Human ovarian cancer

WB 1:1000-1:3000, IHC 1:25-1:100

Polyclonal

IgG

Synthetic peptide of human PAWR

PAWR

2310001G03Rik;PAR 4;PAR-4;Pawr;PAWR;PRKC Apoptosis WT1 Regulator;PRKC apoptosis WT1 regulator protein;Prostate apoptosis response 4 protein;Prostate apoptosis response protein 4;prostate apoptosis response protein PAR-4;Transcriptional repressor Par-4-like protein PAWR;Transcriptional repressor PAR4;WT1 Interacting Protein抗体

Q96IZ0

37kDa

Cytoplasm. Nucleus. Mainly cytoplasmic in absence of apoptosis signal and in normal cells. Nuclear in most cancer cell lines. Nuclear entry seems to be essential but not sufficient for apoptosis (By similarity). Nuclear localization includes nucleoplasm and PML nuclear bodies.

0.7 mg/mL

在-20℃下储存有效期为12个月。 避免冻融循环。

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Affinity purification

Cancer; Cell Biology; Epigenetics and Nuclear Signaling; Metabolism

Unconjugated

The tumor suppressor WT1 represses and activates transcription. The protein encoded by this gene is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells.