LRPAP1 多克隆抗体

Western Blot（WB）已验证样本:293T,Human fetal kidney
免疫组织化学（IHC）已验证样本:Human colon cancer

WB 1:500-1:2000, IHC 1:50-1:200

Polyclonal

IgG

Synthetic peptide of human LRPAP1

LRPAP1

39 kDa receptor-associated protein;A2MRAP;A2RAP;Alpha 2 macroglobulin receptor associated protein;Alpha 2 MRAP;Alpha-2-macroglobulin receptor-associated protein;Alpha-2-MRAP;AMRP;HBP44;Lipoprotein receptor associated protein;Low density lipoprotein receptor related protein associated protein 1;Low density lipoprotein receptor-related protein-associated protein 1;Low density lipoprotein related protein associated protein 1 alpha 2 macroglobulin receptor associated protein;Low density lipoprotein related protein associated protein 1;low density lipoprotein-related protein-associated protein 1 (alpha-2-macroglobulin receptor-associated protein 1);Lrpap1;MGC138272;MRAP;MYP23;RAP抗体

P30533

41kDa

Endoplasmic reticulum. Cytoplasm. Cell surface. Intracellular and associated with cell surface receptors. Found in the endoplasmic reticulum.

1 mg/mL

在-20℃下储存有效期为12个月。 避免冻融循环。

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Affinity purification

Cancer; Cardiovascular; Metabolism; Signal Transduction

Unconjugated

Low density lipoprotein receptor-related protein associated protein 1also known asLRPAP1orRAPis a chaperoneproteinwhich in humans is encoded by the LRPAP1gene. LRPAP1 is involved with trafficking of certain members of the LDL receptor family including LRP1 and LRP2. It is a glycoprotein that binds to the alpha-2-macroglobulin receptor, as well as to other members of the low density lipoprotein receptor family. It acts to inhibit the binding of all know ligands for these receptors, and may prevent receptor aggregation and degradation in the endoplasmic reticulum, thereby acting as a molecular chaperone. It may be under the regulatory control of calmodulin, since it is able to bind calmodulin and be phosphorylated by calmodulin-dependent kinase II.