TAB3 多克隆抗体

Western Blot（WB）已验证样本:293T,RAW264.7,NIH/3T3,K562,Jurkat

WB 1:1000-1:5000

Polyclonal

IgG

Recombinant protein of human TAB3

TAB3

MAP3K7IP 3;Mitogen-activated protein kinase kinase kinase 7-interacting protein 3;NAP1;NF-kappa-B-activating protein 1;NFkB activating protein 1;TAB-3;Tab3;TAB3;TAK1 binding protein 3;TAK1-binding protein 3;TGF-beta-activated kinase 1 and MAP3K7-binding protein 3;TGF-beta-activated kinase 1-binding protein 3抗体

Q8N5C8

79kDa

Cytosol,Endosome membrane,Extracellular region or secreted,extracellular exosome,Plasma Membrane

0.2 mg/mL

在-20℃下储存有效期为12个月。 避免冻融循环。

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Affinity purification

Cancer; Epigenetics and Nuclear Signaling; Immunology; Signal Transduction

Unconjugated

The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene.