Ribosomal Protein L26 Antibody

Ribosomal Protein L26 Antibody

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  • 询价
  • Cell Signaling Technology已认证
  • USA
  • 2025年10月19日
  • W
  • Rabbit
  • H,M,R,Mk
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    • 详细信息
    • 技术资料
    • 抗体英文名

      Ribosomal Protein L26 Antibody

    • 抗原

      synthetic peptide corresponding to the sequence of human ribosomal protein L26

    • 应用范围

      W

    • 宿主

      Rabbit

    • 级别

      详见MSDS文件

    • 供应商

      CST

    • 适应物种

      H,M,R,Mk

    • 保质期

      详见说明书

    • 库存

      大量

    • 是否单克隆

      2

    • 保存条件

      -20°c

    • 规格

      100 ul (10 western blots)/carrier free & custom formulation / quantity

    规格:产品价格:¥请询价
    规格:100 ul (10 western blots)产品价格:¥请询价
    规格:carrier free & custom formulation / quantity产品价格:¥请询价

    pathway more info application references datasheet PDF MSDS PDF protocols

    Applications Key:  W=Western Blotting
    Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Monkey
    Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.

    Applications Reactivity Sensitivity MW (kDa) Source
    W H M R Mk Endogenous 17 Rabbit
    Protocols
    Specificity / Sensitivity

    Ribosomal Protein L26 Antibody detects endogenous levels of total ribosomal protein L26.

    Source / Purification

    Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the sequence of human ribosomal protein L26. Antibodies are purified by protein A and peptide affinity chromatography.

    Western Blotting

    Western Blotting

    Western blot analysis of extracts from various cell types using Ribosomal Protein L26 Antibody.

    Background

    Ribosomal protein L26 (RPL26) is a component of the 60S ribosomal subunit and is involved in translation (1,2). It was shown that RPL26 increases the translation of p53 mRNA by binding to its 5' untranslated region (UTR) after DNA damage. Studies found that overexpression of RPL26 enhances the binding of p53 mRNA to the ribosomes and increases p53 translation. Overexpression of RPL26 also induces cell-cycle arrest at G1 phase and increases radiation-stimulated apoptosis (2).

    1. Odintsova, T.I. et al. (2003) J Protein Chem 22, 249-58.
    2. Takagi, M. et al. (2005) Cell 123, 49-63.
    Application References

    Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know !

    Companion Products

    For Research Use Only. Not For Use In Diagnostic Procedures.

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