AADAC 蛋白, Human (His-SUMO)

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AADAC Protein, Human (His-SUMO)

MCE 国际站：AADAC Protein, Human (His-SUMO)

AADAC, Human (His-SUMO) 是一种在内质网起作用的酯酶，参与多种药物的水解。 AADAC, Human 过度表达可改变多种血管平滑肌细胞特性并减少鼠心血管疾病。

Synonyms: AAAD_HUMAN; Aada; Aadac; Arylacetamide deacetylase esterase; ; Arylacetamide deacetylase; CES5A1; DAC

Species: Human

Source: E. coli

Biological Activity: The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

研究背景：Arylacetamide deacetylase (AADAC) is the major enzyme responsible for the hydrolysis of various clinical drugs, such as flutamide, phenacetin, rifamycins, indiplon, prasugrel, and ketoconazole. AADAC is expressed in the human liver and gastrointestinal tract. AADAC is conserved in animal species, including mice, rats, dogs, and monkeys, although mice and rats have multiple Ces1 and Ces2 isoforms. It has been reported that the expression level of dog CES1 and CES2 in the intestine is much lower than that in the liver. AADAC overexpression alters multiple vascular smooth muscle cells properties and decreases murine cardiovascular disease.

蛋白编号：P22760 (P24-L399)

基因 ID：13

产品分类：酶和调节子  |  水解酶

Categories：Enzymes & Regulators  |  Hydrolases (EC 3)

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