p,p'-DDD

DDT的代谢物；ERα和ERβ的激动剂（REC20s分别为3.2和2.4µM）；抑制DHT诱导的雄激素受体转录(RIC20=0.71µM)；在100和150µg/ml浓度下增加分离的人PBMCs中的细胞凋亡；对仓鼠无致死性（LD50=~5,000mg/kg），但对大鼠有致死性（LD50=3,750mg/kg）。A metabolite of DDT; an agonist at ERα and ERβ (REC20s = 3.2 and 2.4 µM, respectively); inhibits DHT-induced androgen receptor transcription (RIC20 = 0.71 µM); increases apoptosis in isolated human PBMCs at 100 and 150 µg/ml; not considered lethal to hamsters (LD50 = ~5,000 mg/kg) but is to rats (LD50 = 3,750 mg/kg).