产品介绍:The pGL4.16[luc2CP/Hygro] Vector(a–d) encodes the luciferase reporter gene luc2CP (Photinus pyralis) and is designed for high expression and reduced anomalous transcription. This vector also contains a mammalian selectable marker for hygromycin resistance in which the number of transcription factor-binding sites has been reduced and mammalian codon usage optimized. This vector is also engineered with fewer consensus regulatory sequences for reduced background and a decreased risk of anomolous transcription and has a synthetic reporter gene that is codon-optimized for mammalian expression. The pGL4.16[luc2CP/Hygro] Vector is a basic vector with no promoter. However, the vector contains a multiple cloning region to allow cloning of a promoter of choice. The luc2CP reporter gene contains two protein destabilization sequences: hCL1 and hPEST. The protein encoded by luc2CP responds more quickly and with greater magnitude to changes in transcriptional activity than the luc2 gene, its more stable counterpart.