产品说明(Description) Recombinant Mouse Aminopeptidase N is produced by our Mammalian expression system and the target gene encoding Lys69-Ser966 is expressed with a 6His tag at the C-terminus. Accession #: P97449 Known as: Aminopeptidase N; ANPEP; AP-M; APN; AP-N; CD13 antigen; CD13; CD13APN; PEPN; PEPNhAPN
制剂(Formulation) Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
质量控制(Quality Control)
Mol Mass: 103.6kDa AP Mol Mass: 110-130kDa, reducing conditions. Purity: Greater than 95% as determined by reducing SDS-PAGE. Endotoxin: NA
运输(Shipping) The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.
保存(Storage) Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
背景(Background) ANPEP gene encodes aminopeptidase N (APN) also known as microsomal aminopeptiase, alanyl aminopeptidase, aminopeptidase M, CD13, or membrane protein p161, is a member of the peptidase M1 family. Widely expressed in many cells, tissues and species, APN cleaves the N-terminal amino acids from bioactive peptides, leading to their inactivation or degradation. Probably plays a role in regulating growth and differentiation of early B-lineage cells. It also may play a role in the catabolic pathway of the renin-angiotensin system. It degrades vasoconstricting angiotensin II into angiotensin III and therefore helps to regulate blood pressure.