Emivirine,149950-60-7

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Emivirine

CAS No. : 149950-60-7

MCE 国际站：Emivirine

产品活性：Emivirine (MKC-442) 是有效的非核苷逆转录酶的抑制剂 (NNRTIs)，对dTTP 和 dGTP 依赖性 DNA 或 RNA 聚合酶活性的 K_i 值分别为 0.20 和 0.01 μM。Emivirine 具有有效且选择性的抗 HIV-1 活性。

研究领域：Anti-infection

作用靶点：HIV

In Vitro: Emivirine (EMV) is also specific for HIV-1 RT and was without effect on HIV-2.
Emivirine (EMV) has no obvious toxicity for human healthy cells.

In Vivo: Tthe approximate lethal oral dose of Emivirine (EMV) for rats was ≥3 g/kg for males and 2.5 g/kg for females.

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