α2δ ligand 1,313653-15-5

常见的T细胞是αβ T细胞，那γδ T细胞又是什么细胞？

“小众”的一类T细胞 我们常说的T细胞其实是指αβ T细胞，占T细胞群体的65%-70%，其表面的T细胞受体（TCRs）由两条糖蛋白链组成，α链和β链。而γδ T细胞是T细胞的一个亚群，占所有T淋巴细胞的0.5%-5%，其TCRs由γ链和δ链组成，主要存在于上皮和粘膜组织，比如皮肤、肠道等[2]。与传统的αβ T细胞不同，γδ T细胞能识别其目标抗原而不受MHC与限制，并介导抗肿瘤反应，而不会引起移植物抗宿主病（GvHD）[3]。 γδ T细胞是异质性的T细胞，根据其TCRs组成和细胞

Ligand-Binding Assays for Collagen

Collagen is one of the most physiologically important agonists for platelet function. Two collagen-specific receptors, integrin α2 β1 and glycoprotein (GP) VI, have been identified on the platelet surface from studying patient’s platelets

Ligand-Binding Assays: Fibrinogen

The fibrinogen receptor on platelets is glycoprotein (GP) IIb/IIIa, also known as αIIb β3 . This receptor can bind to immobilized fibrinogen in its resting state. Binding to soluble fibrinogen, however, requires activation of the receptor