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- 文献和实验
- 技术资料
- 保存条件:
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
1219805-99-8
- 规格:
1 mg
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Doxofylline-d6
CAS No. : 1219805-99-8
MCE 国际站:Doxofylline-d6
产品活性:Doxofylline-d6 是 Doxofylline 的氘代物。Doxofylline 是腺苷 A1 受体 (adenosine A1 receptor) 的拮抗剂,且能抑制磷酸二酯酶 IV (phosphodiesterase IV)。
研究领域:GPCR/G Protein | Metabolic Enzyme/Protease
作用靶点:Adenosine Receptor | Phosphodiesterase (PDE)
In Vitro: Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
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文献和实验【摘要】 目的提取鉴定毛泡桐叶中的乌索酸,并建立其含量测定方法。方法采用“醇提凝析法”新工艺分离制备乌索酸,IR,MS,NMR 鉴定其结构。建立反相高效液相色谱测定其含量的方法,色谱柱为 KromasilC18 柱,流动相为乙腈-甲醇-水-磷酸(体积比168∶682∶150∶1.68),流速0.8 ml/min,检测波长210 nm,柱温25℃。结果乌索酸在0.92~16.56 μg范围内线性关系良好(r=0.999 6)。样品乌索酸含量为99.61%,得率为30.5%。结论
1+/inft69etoeBivlK9gAA6+iPbKxGaXXiEcWECiiDAmg9FUOYxIFwCJ44fB2EAuu/A4WSLIir6XbVyOaz37cWBg4dRq1Ytps0EMi2Bo0ePYsTIkahRoxY6duoco7v6xQvncfDgfgTQcZ8QPCIX4d6+iuJ9jKQ+ElpeU24ZESCQNY4JJZc567PmI3Puu0JXLVJ99+/bW8qqecTmZLIJHr9+/ULfXj1gd/sWHjx8zIKHQneVB0uLBDp06IBnFKjP
cell neuroendocrine carcinomas of other sites.- Use of CK7 and CK20 together is of great help in predicting the likely origin of a carcinoma, especially adenocarcinoma (Wang et al, Appl Immunohistochem 1995;3:99-107; Chu et al, Mod Pathol 2000;13:962
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