(S)-1-(5-溴吡啶-2-基)乙胺,(S)-1-(5-B

泛酰巯基乙胺pantetheine，pantotheine

作为乳酸菌Lactobacillus bulgaricus、L.helv- eficus等的生育因子（LB因子Lactobacillus bulgari- cus factor）是由E.E.Snell等所发现的（1949）。由泛酸与β-巯基乙胺缩合而成。末端具有-SH基，被氧化后形成二分子带有S-S键的氧化型，这种氧化型称双泛酰硫乙胺。但天然并不存在这种形式，似乎是与半胱氨酸和谷胱甘肽相结合而存在。泛酰巯基乙胺与三分子磷酸和腺苷相结合便形成CoA。用磷酸酶使CoA部分水解就产基巯泛生酰

Two‐Step, One‐Pot Synthesis of Inosine, Guanosine, and 2′‐Deoxyguanosine O6‐Ethers via Intermediate O6‐(Benzotriazol‐1‐yl) Derivatives

N‐/purin‐6‐yl/pyridinium salts. Nucleic Acids Res. 13:2989‐3003.    Allerson, C.R., Chen, S.L., and Verdine, G.L. 1997. A chemical method for site‐specific modification

Oligodeoxynucleotide Containing S‐Functionalized 2′‐Deoxy‐6‐Thioguanosine: Facile Tools for Base‐Selective and Site‐Specific Internal Modification of

Table of Contents Introduction Basic Protocol 1: Preparation of Dimethoxytrityl‐Protected Phophoramidite of S‐Protected 2′‐Deoxy‐6‐Thioguanosine from 2′