2-(((苄氧基)羰基)氨基)-2-(二甲氧基磷酰基)乙酸苄

组织蛋白酶cathepsin

组织蛋白酶 cathepsin 在各种动物组织的细胞内（特别是溶酶体部分）发现的一类蛋白酶。此名源自希腊语的“消化”，为威尔斯达特（ R． Willstā atter， 1929）命名的。来源于同一种类组织细胞的也是由组织蛋白酶 A． B． C． D． E等多种酶组成。可以根据所作用的代表性底物的种类进行分类，但似乎各自还有数种同工酶。组织蛋白酶 A的代表性底物是 N-苄氧基羰基 -L-谷酰胺 -L-苯丙氨酸，最适 pH约 5.5（ 3— 6），可能是一种羧肽酶，可为二异丙基磷氟酸

Immunohistochemical Detection of Protein Oxidation

, almost all oxidative modifications of proteins are resulting in an increase of carbonylated proteins. The three major pathways leading to carbonyl group formation (protein oxidation) are shown in Fig. 1 . Carbonyl groups are introduced into proteins as a result

Asymmetric Syntheses of Unnatural Amino Acids and Hydroxyethylene Peptide Isosteres

Unnatural and naturally occurring nonproteinogenic α-amino acids have become important building blocks for the synthesis of biologically active peptides and peptidomimetic drug molecules. The asymmetric synthesis of α-amino acids