- ￥1125 - 1875
- HuaBio/华安生物
- RT1557
- 2025年07月13日
- WB, IP, IF
- Mouse
- Human, Mouse, Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
peptide
- 亚型：
IgG1
- 形态：
Liquid
- 克隆性：
Mouse monoclonal Antibody
- 标记物：
Non-conjugated
- 适应物种：
Human, Mouse, Rat
- 库存：
现货
- 供应商：
华安生物
- 宿主：
Mouse
- 应用范围：
WB, IP, IF
- 浓度：
2 mg/mL.
- 规格：
50ul/100ul
| 规格： | 50ul | 产品价格： | ￥1125.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1875.0 |
The frizzled gene was originally identified in Drosophila melanogaster and was shown to be involved in the development of tissue polarity. The mammalian homolog of frizzled, as well as several mammalian frizzled-related proteins, FRP-1 (also designated SARP2), FRP-2 (also designated SARP1), FRP-3 and SARP3 (also designated FRP-5) have been identified. Frizzled is a transmem- brane protein that functions as a receptor for Wnt. The frizzled related proteins FRP-1, FRP-2, FRP-3 and SARP3 are secreted proteins that contain regions of homology to the cysteine-rich ligand-binding domain of frizzled. The FRPs/ SARPs have also been shown to be involved in the Wnt signaling pathway by regulating the intracellular levels of β-catenin.
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文献和实验相关实验
v468.Chapter 3 分泌型跨膜相关蛋白提纯及Wnt抑制活性
. Cell 124 , 147–159. 4. Rodriguez, J., Esteve, P., Weinl, C., Ruiz,J.M., Fermin, Y., Trousse, F., et al. (2005)SFRP1 regulates the growth of retinal ganglioncell axons through the Fz2 receptor. Nat. Neurosci. 8 , 1301–1309. 5. Hoang, B., Moos, M
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SFRP1
￥1125 - 1875
