- ￥1125 - 1875
- HuaBio/华安生物
- R1512-15
- 2025年07月09日
- WB, ICC, IHC-P, FC
- Rabbit
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Synthetic peptide corresponding toHuman GPC1 aa 1-50 / 558.
- 亚型：
IgG
- 形态：
Liquid
- 克隆性：
Rabbit polyclonal Antibody
- 标记物：
Non-conjugated
- 适应物种：
Human
- 库存：
现货
- 供应商：
华安生物
- 宿主：
Rabbit
- 应用范围：
WB, ICC, IHC-P, FC
- 浓度：
1 mg/mL.
- 规格：
50ul/100ul
| 规格： | 50ul | 产品价格： | ￥1125.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1875.0 |
Glypican-1 (GPC1), a member of the glycosylphosphatidilinositol anchored cell surface heparan sulfate proteoglycans, is involved with cell adhesion and migration, lipoprotein metabolism, modulation of growth factor activites and anticoagulation. Glypican-1 binds to and modulates the activity of several fibroblast growth factors (FGFs) including FGF-1, FGF-2 and FGF-7. Glypican-1 acts as an extracellular chaperone for VEGF165 to help restore receptor binding ability after oxidation. The heparan sulfate chains of glypican-1 mediate specific binding of glypican-1 to VEGF165. When present on the surface of marrow stromal cells, glypican-1 may aid in the maintenance and development of hematopoietic stem and progenitor cells. Human pancreatic cancer cells express a large amount of glypican-1 when compared to glypican-1 levels in normal pancreatic cells. Glypican-1 may play an important role in the response of pancreatic cancer cells to mitogenic stimuli, such as FGF-2. The gene encoding human glypican-1 maps to chromosome 2q37.3.
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文献和实验相关实验
-GlyTCC-5、tRNA-ValAAC-5 和 tRNA-GluCTC-5)的水平显著升高，这表明血浆外泌体tsRNA可以作为一种新的诊断生物标志物。 图四 细胞培养上清外泌体的 tsRNAs 谱 图五 血浆外泌体的 tsRNAs 谱 三、以外泌体蛋白为标志物： Raghu Kalluri 教授与他的研究团队发表研究论文[3]，阐明胰腺癌患者血清中外泌体表达了一种特殊的蛋白 glypican-1 (GPC1)，而在健康人和胰腺其他疾病血清外泌体中没有检测到 GPC1
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GPC1
￥1125 - 1875
