Recombinant protein within human Alpha-2-macroglobulin aa 950-1200.
亚型:
IgG2c
形态:
Liquid
克隆性:
Mouse monoclonal Antibody
标记物:
Non-conjugated
适应物种:
Human
库存:
现货
供应商:
华安生物
宿主:
Mouse
应用范围:
IHC-P,ELISA
浓度:
2 mg/mL.
规格:
50ul/100ul
规格:
50ul
产品价格:
¥1125.0
规格:
100ul
产品价格:
¥1875.0
Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region, a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.