- ￥1125 - 1875
- HuaBio/华安生物
- M1008-10
- 2025年07月16日
- WB, IHC-P, FC
- Mouse
- Human, Mouse, Rat
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- 详细信息
- 技术资料
- 免疫原：
Recombinant protein within Human FAM3A 1-230 / 230.
- 亚型：
IgG1
- 形态：
Liquid
- 克隆性：
Mouse monoclonal Antibody
- 标记物：
Non-conjugated
- 适应物种：
Human, Mouse, Rat
- 库存：
现货
- 供应商：
华安生物
- 宿主：
Mouse
- 应用范围：
WB, IHC-P, FC
- 浓度：
2 mg/mL.
- 规格：
50ul/100ul
| 规格： | 50ul | 产品价格： | ￥1125.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1875.0 |
The FAM3 gene family is a novel cytokine-like gene family, which includes four members designated as FAM3A, FAM3B, FAM3C, and FAM3D. FAM3A is a secreted protein belonging to the FAM3 family of four alpha -helix bundle cytokines. It is expressed in multiple tissues. Mature human FAM3A shares approximately 93% amino acid sequence identity with the mouse and rat protein.FAM3A belongs to a novel cytokine-like gene family, and its physiological role remains largely unknown. FAM3A activated Akt through the p110α catalytic subunit of PI3K in an insulin-independent manner. Blockade of P2 ATP receptors or downstream phospholipase C (PLC) and IP3R and removal of medium calcium all significantly reduced FAM3A-induced increase in cytosolic free Ca2+ levels and attenuated FAM3A-mediated PI3K/Akt activation. Moreover, FAM3A-induced Akt activation was completely abolished by the inhibition of calmodulin (CaM).
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FAM3A
￥1125 - 1875
