ACAA2

ACAA2 Antibody (192) is a high quality monoclonal ACAA2 antibody (also designated ACAA2 antibody) suitable for the detection of the ACAA2 protein of mouse, rat and human origin. ACAA2 Antibody (192) is available as the non-conjugated anti-ACAA2 antibody. Mammalian tissues contain five types of thiolases, all of which participate in metabolism of various compounds throughout the body. ACAA2 (acetyl-Coenzyme A acyltransferase 2), also known as DSAEC, is a 397 amino acid member of the thiolase family of enzymes and is involved in lipid metabolism. Localized to the mitochondrion, ACAA2 catalyzes the last step, namely the conversion of acetyl-CoA to 3-oxoacyl-CoA, in the fatty acid oxidation pathway. ACAA2 is highly expressed in liver, fibrofblasts and intercostal muscle and contains an N-terminal targeting signal that, unlike other mitochondrial proteins, is non-cleavable. Human ACAA2 shares 86.6% amino acid identity with its rat counterpart, suggesting a conserved function for ACAA2 among different species.