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RelB

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  • ¥1125 - 1875
  • HuaBio/华安生物
  • 华安生物
  • ET1612-18
  • 2025年07月15日
  • WB, ICC/IF, IHC-P, IP
  • Rabbit
  • Human
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      Synthetic peptide within Human RelB aa 1-50 / 579.

    • 亚型

      IgG

    • 形态

      Liquid

    • 克隆性

      Recombinant Rabbit monoclonal Antibody

    • 标记物

      Non-conjugated

    • 适应物种

      Human

    • 库存

      现货

    • 供应商

      华安生物

    • 宿主

      Rabbit

    • 应用范围

      WB, ICC/IF, IHC-P, IP

    • 浓度

      1 mg/mL.

    • 规格

      50μl/100μl

    规格:50μl产品价格:¥1125.0
    规格:100μl产品价格:¥1875.0
    The NFκB transcription factor was originally identified as a protein complex consisting of a DNA binding subunit and an associated protein. The DNA binding subunit is functionally related to c-Rel p75 and Rel B p68. The p50 subunit was initially believed to be a functionally unique protein derived from the amino terminus of a precursor designated p105. A second protein designated p52 (previously referred to as p49) has been identified that can act as an alternative NFκB subunit. Rel B does not bind with high affinity to NFkB sites, but heterodimers between Rel B and p50 bind with an affinity comparable to that of p50 NFκB homodimers. However, Rel B/p50 heterodimers, in contrast to NFκB heterodimers, transactivates transcription of promotors containing κB binding sites.

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    图标文献和实验
    相关实验
    • Preventing Immune Rejection Through Gene Silencing

      that DC maturation is associated with activation of the NF-κB pathway. RelB, one of the five families of Rel proteins involved in the NF-κB pathway, plays a critical role in coordinating the terminal stages of DC maturation and has the ability to induce

    • 【进展|热点】Nature Immunology:发现三个调控NF-kB非经典信号通路的microRNA

      ://www.nature.com/ni/journal/v11/n9/abs/ni.1918.html 内容简介: NF-κB是一组重要的转录因子,参与了诸多免疫反应过程,其中最为人熟知的就是在天然免疫中,NF-κB是最终启动炎症因子表达的因素之一。 NF-κB家族包括5个成员,即RelA(p65)、RelB、c-Rel、p105-p50(NF-κB1)和p100-p52(NF-κB2),两两形成同源或者异源二聚体的形式发挥作用。通常情况下,NF-κB与其抑制蛋白IκB(包括IκBα、IκBβ

    • Activation of Nuclear Factor-B (NF-B) in Mononuclear Cells (MNC)

      is a heterodimer, which usually consists of two proteins, a p65 (relA) subunit and a p50 subunit. Other subunits (rel, relB, v-rel, and p52) can also bind to the activated NF-κB and thus can activate different sets of genes.

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