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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
The antiserum was produced against synthesized peptide derived from human ZEB2. AA range:71-120
- 亚型:
IgG
- 形态:
Liquid
- 克隆性:
Rabbit polyclonal Antibody
- 标记物:
Non-conjugated
- 适应物种:
Human, Mouse, Rat
- 库存:
现货
- 供应商:
华安生物
- 宿主:
Rabbit
- 应用范围:
WB, IHC-P
- 浓度:
1 mg/mL.
- 规格:
50μl/100μl
| 规格: | 50μl | 产品价格: | ¥1125.0 |
|---|---|---|---|
| 规格: | 100μl | 产品价格: | ¥1875.0 |
SMAD regulates gene expression by interacting with different classes of transcription factors including DNA-binding multi-zinc finger proteins. ZEB2 (zinc finger E-box-binding protein 2) is a member of the delta-EF1/Zfh1 family of 2-handed zinc finger/homeodomain proteins. ZEB2 contains a SMAD-binding domain, a homeodomain and two clusters of zinc fingers on the N- and C-termini. ZEB2, also known as SMADIP1, ZFHX1B and SIP1 (SMAD interacting protein 1), may be induced by TGFβ treatment. ZEB2 plays a crucial role in normal embryonic development of neural structures and neural crest. The human ZEB2 gene maps to chromosome 2q22. Mutations in the ZEB2 gene cause a form of Hirschsprung disease (HSCR). Patients with ZEB2 mutations show mental retardation, delayed motor development, epilepsy, microcephaly, distinct facial features and/or congenital heart disease, all symptoms of HSCR.
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文献和实验相关实验
modification(SIP1) . Comparablely micoRNAs were the most understanded . microRNAs’ target site mutations could enhance or reduce the gene expression profiles , paticular in cancers . Not only the UTR mutations but the CDS of genes were linked
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SIP1
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