The antiserum was produced against synthesized peptide derived from human DLGAP5. AA range:791-840
亚型:
IgG
形态:
Liquid
克隆性:
Rabbit polyclonal Antibody
标记物:
Non-conjugated
适应物种:
Human
库存:
现货
供应商:
华安生物
宿主:
Rabbit
应用范围:
WB
浓度:
1 mg/mL.
规格:
50μl/100μl
规格:
50μl
产品价格:
¥1125.0
规格:
100μl
产品价格:
¥1875.0
developmental stage:Elevated levels of expression detected in the G2/M phase of synchronized cultures of HeLa cells. Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells. PTM:Phosphorylated upon DNA damage, probably by ATM or ATR. Decreased phosphorylation levels are associated with the differentiation of intestinal epithelial cells. PTM:Ubiquitinated, leading to its degradation. Belongs to the SAPAP family. subcellular location:Localizes to the spindle poles in mitotic cells. Colocalizes with CDH1 at sites of cell-cell contact in intestinal epithelial cells. subunit:Interacts with CDC2. Interacts with the C-terminal proline-rich region of FBXO7. Recruited by FBXO7 to a SCF (SKP1-CUL1-F-box) protein complex in a CDC2/Cyclin B-phosphorylation dependent manner. Interacts with CDH1. tissue specificity:Abundantly expressed in fetal liver. Expressed at lower levels in bone marrow, testis, colon, and placenta.