- ￥1125 - 1875
- HuaBio/华安生物
- 华安生物
- ER1915-89
- 2025年10月19日
- WB
- Rabbit
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep
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- 详细信息
- 技术资料
- 免疫原：
KLH conjugated synthetic peptide derived from human RNF12 525-624/624
- 亚型：
IgG
- 形态：
Liquid
- 克隆性：
Rabbit polyclonal Antibody
- 标记物：
Non-conjugated
- 适应物种：
Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep
- 库存：
现货
- 供应商：
华安生物
- 宿主：
Rabbit
- 应用范围：
WB
- 浓度：
1 mg/mL.
- 抗体名：
RNF12
- 规格：
50μl/100μl
| 规格： | 50μl | 产品价格： | ￥1125.0 |
|---|---|---|---|
| 规格： | 100μl | 产品价格： | ￥1875.0 |
E3 ubiquitin-protein ligase. Acts as a negative coregulator for LIM homeodomain transcription factors by mediating the ubiquitination and subsequent degradation of LIM cofactors LDB1 and LDB2 and by mediating the recruitment the SIN3a/histone deacetylase corepressor complex. Ubiquitination and degradation of LIM cofactors LDB1 and LDB2 allows DNA-bound LIM homeodomain transcription factors to interact with other protein partners such as RLIM. Plays a role in telomere length-mediated growth suppression by mediating the ubiquitination and degradation of TERF1. By targeting ZFP42 for degradation, acts as an activator of random inactivation of X chromosome in the embryo, a stochastic process in which one X chromosome is inactivated to minimize sex-related dosage differences of X-encoded genes in somatic cells of female placental mammals.
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RNF12
￥1125 - 1875
