- ￥1125 - 1875
- HuaBio/华安生物
- 华安生物
- ER1912-42
- 2025年10月11日
- WB, IHC-P, FC
- Rabbit
- Human, Mouse, Rat, Cow, Rabbit
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- 详细信息
- 技术资料
- 免疫原：
KLH conjugated synthetic peptide derived from rabbit LOX-1 201-273/273
- 亚型：
IgG
- 形态：
Liquid
- 克隆性：
Rabbit polyclonal Antibody
- 标记物：
Non-conjugated
- 适应物种：
Human, Mouse, Rat, Cow, Rabbit
- 库存：
现货
- 供应商：
华安生物
- 宿主：
Rabbit
- 应用范围：
WB, IHC-P, FC
- 浓度：
1 mg/mL.
- 抗体名：
LOX 1
- 规格：
50μl/100μl
| 规格： | 50μl | 产品价格： | ￥1125.0 |
|---|---|---|---|
| 规格： | 100μl | 产品价格： | ￥1875.0 |
-
概述
- 产品描述Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis. In addition to binding oxLDL, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, thereby participating in cell-mediated antigen cross-presentation. Also involved in inflammatory process, by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation. Also acts as a receptor for advanced glycation end (AGE) products, activated platelets, monocytes, apoptotic cells and both Gram-negative and Gram-positive bacteria.
- 产品名称Anti-LOX 1 antibody
- 分子量31/50 KDa
- 种属反应性Human, Mouse, Rat, Cow, Rabbit
- 验证应用WB, IHC-P, FC
- 抗体类型兔多抗
- 免疫原KLH conjugated synthetic peptide derived from rabbit LOX-1 201-273/273
- 偶联Non-conjugated
-
性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
- 存储缓冲液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 亚型IgG
- 纯化方式Protein A affinity purified.
- 亚细胞定位Cell membrane; Single-pass type II membrane protein. Secreted. Note=A secreted form also exists.
- 数据链接SwissProt: P78380 Human
SwissProt: Q9EQ09 Mouse - 其它名称
- Lectin-type oxidized LDL receptor 1
- OLR1
- lectin-like low density lipoprotein receptor-1
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技术资料暂无技术资料 索取技术资料
LOX 1
￥1125 - 1875
