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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
KLH conjugated synthetic peptide derived from human GPR54 121-200/398
- 亚型:
IgG
- 形态:
Liquid
- 克隆性:
Rabbit polyclonal Antibody
- 标记物:
Non-conjugated
- 适应物种:
Human, Mouse, Rat, Dog, Pig, Sheep, Guinea pig
- 库存:
现货
- 供应商:
华安生物
- 宿主:
Rabbit
- 应用范围:
WB
- 浓度:
1 mg/mL.
- 抗体名:
KiSS1 receptor
- 规格:
50μl/100μl
| 规格: | 50μl | 产品价格: | ¥1125.0 |
|---|---|---|---|
| 规格: | 100μl | 产品价格: | ¥1875.0 |
-
概述
- 产品描述Receptor for metastin (kisspeptin-54 or kp-54), a C-terminally amidated peptide of KiSS1. KiSS1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some breast carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. The receptor is essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/KISS1R system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. The receptor is also probably involved in the regulation and fine-tuning of trophoblast invasion generated by the trophoblast itself. Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins.
- 产品名称Anti-KiSS1 receptor antibody
- 分子量44 KDa
- 种属反应性Human,Mouse,Rat,Dog,Pig,Sheep,Guinea Pig
- 验证应用WB
- 抗体类型兔多抗
- 免疫原KLH conjugated synthetic peptide derived from human GPR54 121-200/398
- 偶联Non-conjugated
-
性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
- 存储缓冲液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 亚型IgG
- 纯化方式Protein A affinity purified.
- 亚细胞定位Cell membrane; Multi-pass membrane protein.
- 数据链接SwissProt: Q969F8 Human
- 其它名称
- AXOR 12
- AXOR12
- G protein coupled receptor 54
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